STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDFY3WD repeat and FYVE domain containing 3. (3609 aa)    
Predicted Functional Partners:
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
   
 0.782
PLEKHG7
Pleckstrin homology and RhoGEF domain containing G7.
    
 0.719
AUTS2
Activator of transcription and developmental regulator AUTS2.
      
 0.701
ATP6V0A2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
 0.686
PISD
Phosphatidylserine decarboxylase.
   
  
 0.686
SQSTM1
Sequestosome 1.
   
 
 0.678
ATG12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
   
 0.674
TBC1D19
TBC1 domain family member 19.
   
  
 0.667
GABARAP
GABA type A receptor-associated protein.
   
 
 0.647
WDFY2
WD repeat and FYVE domain containing 2.
   
  
 0.641
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.