STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC2Rac family small GTPase 2. (192 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 
 0.996
NCF2
Neutrophil cytosolic factor 2.
   
 0.995
NCF1
Neutrophil cytosolic factor 1.
   
 0.994
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.988
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 0.984
PAK1
Non-specific serine/threonine protein kinase.
   
 0.974
NCF4
Neutrophil cytosolic factor 4.
   
 0.973
NCKAP1
NCK associated protein 1.
   
 0.972
PREX1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
   
 0.971
VAV2
Vav guanine nucleotide exchange factor 2.
   
 0.971
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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