STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-1NK2 homeobox 1. (610 aa)    
Predicted Functional Partners:
SFTPB
Surfactant protein B.
   
  
 0.827
SFTPC
Surfactant protein C.
   
  
 0.808
PAX8
Paired box 8.
   
 
 0.689
LHX6
LIM homeobox 6.
   
 
 0.666
FOXA2
Forkhead box A2.
   
 
 0.620
TG
Thyroglobulin.
      
 0.612
FOXA1
Forkhead box A1.
  
 
 0.603
FOXE1
Forkhead box E1.
   
 
 0.585
TSHR-2
Uncharacterized protein.
      
 0.573
SFTPA1
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
   
  
 0.572
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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