STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPYPancreatic polypeptide; Belongs to the NPY family. (104 aa)    
Predicted Functional Partners:
SST
Somatostatin.
     
 0.980
CEL
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
 0.959
UMOD
Uromodulin.
   
  0.956
GHRL
Ghrelin and obestatin prepropeptide.
   
  
 0.955
CPA1
Carboxypeptidase A1.
   
  
 0.953
LOC100071692
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.949
LOC100050670
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
  
 0.948
GH1
Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family.
   
  
 0.940
PYY
Peptide YY.
   
 
 0.868
GCG
Glucagon.
   
 
 0.828
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.