STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRED2Sprouty related EVH1 domain containing 2. (417 aa)    
Predicted Functional Partners:
SPRED1
Sprouty related EVH1 domain containing 1.
  
  
0.890
NF1
Neurofibromin 1.
    
 0.884
FGFRL1
Fibroblast growth factor receptor like 1.
   
 
 0.701
KIAA1217
KIAA1217.
    
 
 0.652
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
      
 0.623
STAM
Signal transducing adaptor molecule.
      
 0.600
NEK2
NIMA related kinase 2.
    
 0.600
KSR1
Kinase suppressor of ras 1.
    
 
 0.594
STAM2
Signal transducing adaptor molecule 2.
      
 0.565
NCAPH
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
      
 0.531
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.