SPARC protein (Equus caballus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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[Homology]

Score

SPARC

Secreted protein acidic and cysteine rich. (313 aa)

Predicted Functional Partners:

LUM

0.977

COL1A2

0.970

ALB

0.958

COL1A1

0.955

DCN

0.920

APOB

0.898

SPP1

0.879

STAB1

0.854

BGLAP

0.835

COL3A1

0.719

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	APOB	ENSECAP00000041304	ENSECAP00000036863	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Apolipoprotein B.	0.821
ALB	BGLAP	ENSECAP00000041304	ENSECAP00000021446	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	0.596
ALB	COL1A1	ENSECAP00000041304	ENSECAP00000054911	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Collagen type I alpha 1 chain.	0.599
ALB	COL1A2	ENSECAP00000041304	ENSECAP00000022567	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Collagen type I alpha 2 chain.	0.425
ALB	COL3A1	ENSECAP00000041304	ENSECAP00000022362	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Collagen type III alpha 1 chain.	0.416
ALB	DCN	ENSECAP00000041304	ENSECAP00000017861	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.517
ALB	LUM	ENSECAP00000041304	ENSECAP00000015833	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Lumican.	0.598
ALB	SPARC	ENSECAP00000041304	ENSECAP00000038342	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Secreted protein acidic and cysteine rich.	0.958
ALB	SPP1	ENSECAP00000041304	ENSECAP00000014936	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Secreted phosphoprotein 1.	0.672
APOB	ALB	ENSECAP00000036863	ENSECAP00000041304	Apolipoprotein B.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.821
APOB	SPARC	ENSECAP00000036863	ENSECAP00000038342	Apolipoprotein B.	Secreted protein acidic and cysteine rich.	0.898
APOB	STAB1	ENSECAP00000036863	ENSECAP00000008938	Apolipoprotein B.	Stabilin 1.	0.848
BGLAP	ALB	ENSECAP00000021446	ENSECAP00000041304	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.596
BGLAP	COL1A1	ENSECAP00000021446	ENSECAP00000054911	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Collagen type I alpha 1 chain.	0.819
BGLAP	COL1A2	ENSECAP00000021446	ENSECAP00000022567	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Collagen type I alpha 2 chain.	0.518
BGLAP	DCN	ENSECAP00000021446	ENSECAP00000017861	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.648
BGLAP	SPARC	ENSECAP00000021446	ENSECAP00000038342	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Secreted protein acidic and cysteine rich.	0.835
BGLAP	SPP1	ENSECAP00000021446	ENSECAP00000014936	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Secreted phosphoprotein 1.	0.961
COL1A1	ALB	ENSECAP00000054911	ENSECAP00000041304	Collagen type I alpha 1 chain.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.599
COL1A1	BGLAP	ENSECAP00000054911	ENSECAP00000021446	Collagen type I alpha 1 chain.	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	0.819