LIN28B protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LIN28B

Lin-28 homolog B. (258 aa)

Predicted Functional Partners:

TUT4

0.679

HMGA2

0.654

AGBL3

0.650

MRPL11

0.594

DICER1

0.586

NANOG

0.579

DROSHA

0.578

IGF2BP3

0.574

RPS23

0.573

IGF2BP2

0.571

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGBL3	LIN28B	ENSECAP00000030714	ENSECAP00000039063	ATP/GTP binding protein like 3.	Lin-28 homolog B.	0.650
DICER1	DROSHA	ENSECAP00000043526	ENSECAP00000012122	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Drosha ribonuclease III.	0.777
DICER1	LIN28B	ENSECAP00000043526	ENSECAP00000039063	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Lin-28 homolog B.	0.586
DICER1	RPS23	ENSECAP00000043526	ENSECAP00000023304	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.609
DICER1	TUT4	ENSECAP00000043526	ENSECAP00000019142	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	Terminal uridylyl transferase 4.	0.503
DROSHA	DICER1	ENSECAP00000012122	ENSECAP00000043526	Drosha ribonuclease III.	Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily.	0.777
DROSHA	LIN28B	ENSECAP00000012122	ENSECAP00000039063	Drosha ribonuclease III.	Lin-28 homolog B.	0.578
DROSHA	NANOG	ENSECAP00000012122	ENSECAP00000010460	Drosha ribonuclease III.	Homeobox domain-containing protein.	0.936
DROSHA	RPS23	ENSECAP00000012122	ENSECAP00000023304	Drosha ribonuclease III.	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.609
DROSHA	TUT4	ENSECAP00000012122	ENSECAP00000019142	Drosha ribonuclease III.	Terminal uridylyl transferase 4.	0.486
HMGA2	IGF2BP2	ENSECAP00000039603	ENSECAP00000045670	Uncharacterized protein.	Insulin like growth factor 2 mRNA binding protein 2.	0.822
HMGA2	IGF2BP3	ENSECAP00000039603	ENSECAP00000014668	Uncharacterized protein.	Insulin like growth factor 2 mRNA binding protein 3.	0.584
HMGA2	LIN28B	ENSECAP00000039603	ENSECAP00000039063	Uncharacterized protein.	Lin-28 homolog B.	0.654
IGF2BP2	HMGA2	ENSECAP00000045670	ENSECAP00000039603	Insulin like growth factor 2 mRNA binding protein 2.	Uncharacterized protein.	0.822
IGF2BP2	IGF2BP3	ENSECAP00000045670	ENSECAP00000014668	Insulin like growth factor 2 mRNA binding protein 2.	Insulin like growth factor 2 mRNA binding protein 3.	0.468
IGF2BP2	LIN28B	ENSECAP00000045670	ENSECAP00000039063	Insulin like growth factor 2 mRNA binding protein 2.	Lin-28 homolog B.	0.571
IGF2BP3	HMGA2	ENSECAP00000014668	ENSECAP00000039603	Insulin like growth factor 2 mRNA binding protein 3.	Uncharacterized protein.	0.584
IGF2BP3	IGF2BP2	ENSECAP00000014668	ENSECAP00000045670	Insulin like growth factor 2 mRNA binding protein 3.	Insulin like growth factor 2 mRNA binding protein 2.	0.468
IGF2BP3	LIN28B	ENSECAP00000014668	ENSECAP00000039063	Insulin like growth factor 2 mRNA binding protein 3.	Lin-28 homolog B.	0.574
LIN28B	AGBL3	ENSECAP00000039063	ENSECAP00000030714	Lin-28 homolog B.	ATP/GTP binding protein like 3.	0.650