STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCBE1Collagen and calcium binding EGF domains 1. (439 aa)    
Predicted Functional Partners:
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif 3.
   
  
 0.844
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
 0.814
FAM43A
Family with sequence similarity 43 member A.
      
 0.694
SOX18
SRY-box transcription factor 18.
      
 0.607
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
    
 0.588
FAM163A
Family with sequence similarity 163 member A.
      
 0.579
GJC2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.539
FOXC2
Forkhead box protein C2.
     
 0.498
FOXC1
Forkhead box C1.
     
 0.498
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1.
   
 0.493
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.