ACTC1 protein (Equus caballus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

ACTC1

Actin alpha cardiac muscle 1. (377 aa)

Predicted Functional Partners:

TNNT2

0.975

TPM2

0.975

MYL2

0.974

TNNI3

0.971

MYL4

0.969

TPM3

0.966

MYH6

0.962

MYL3

0.955

TPM4

0.944

DCTN2

0.818

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTC1	DCTN2	ENSECAP00000039369	ENSECAP00000035071	Actin alpha cardiac muscle 1.	Dynactin subunit 2.	0.818
ACTC1	MYH6	ENSECAP00000039369	ENSECAP00000049644	Actin alpha cardiac muscle 1.	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.962
ACTC1	MYL2	ENSECAP00000039369	ENSECAP00000006215	Actin alpha cardiac muscle 1.	Myosin light chain 2.	0.974
ACTC1	MYL3	ENSECAP00000039369	ENSECAP00000015141	Actin alpha cardiac muscle 1.	Myosin light chain 3.	0.955
ACTC1	MYL4	ENSECAP00000039369	ENSECAP00000018586	Actin alpha cardiac muscle 1.	Myosin light chain 4.	0.969
ACTC1	TNNI3	ENSECAP00000039369	ENSECAP00000045110	Actin alpha cardiac muscle 1.	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.971
ACTC1	TNNT2	ENSECAP00000039369	ENSECAP00000031919	Actin alpha cardiac muscle 1.	Troponin T2, cardiac type.	0.975
ACTC1	TPM2	ENSECAP00000039369	ENSECAP00000043742	Actin alpha cardiac muscle 1.	Tropomyosin 2; Belongs to the tropomyosin family.	0.975
ACTC1	TPM3	ENSECAP00000039369	ENSECAP00000036765	Actin alpha cardiac muscle 1.	Tropomyosin 3; Belongs to the tropomyosin family.	0.966
ACTC1	TPM4	ENSECAP00000039369	ENSECAP00000047008	Actin alpha cardiac muscle 1.	Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.	0.944
DCTN2	ACTC1	ENSECAP00000035071	ENSECAP00000039369	Dynactin subunit 2.	Actin alpha cardiac muscle 1.	0.818
MYH6	ACTC1	ENSECAP00000049644	ENSECAP00000039369	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Actin alpha cardiac muscle 1.	0.962
MYH6	MYL2	ENSECAP00000049644	ENSECAP00000006215	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 2.	0.979
MYH6	MYL3	ENSECAP00000049644	ENSECAP00000015141	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 3.	0.992
MYH6	MYL4	ENSECAP00000049644	ENSECAP00000018586	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Myosin light chain 4.	0.992
MYH6	TNNI3	ENSECAP00000049644	ENSECAP00000045110	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.869
MYH6	TNNT2	ENSECAP00000049644	ENSECAP00000031919	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Troponin T2, cardiac type.	0.919
MYH6	TPM2	ENSECAP00000049644	ENSECAP00000043742	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Tropomyosin 2; Belongs to the tropomyosin family.	0.925
MYH6	TPM3	ENSECAP00000049644	ENSECAP00000036765	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Tropomyosin 3; Belongs to the tropomyosin family.	0.929
MYH6	TPM4	ENSECAP00000049644	ENSECAP00000047008	Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Tropomyosin alpha-4 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.	0.544