ARHGAP27 protein (Equus caballus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ARHGAP27

Rho GTPase activating protein 27. (1047 aa)

Predicted Functional Partners:

PLEKHM1

0.710

RDM1

0.697

CLNK

0.688

WDFY4

0.586

VPS13D

0.568

CYTIP

0.568

MYO9B

0.530

MYO9A

0.528

MRPS24

0.525

NSMAF

0.522

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP27	CLNK	ENSECAP00000039414	ENSECAP00000024317	Rho GTPase activating protein 27.	Cytokine dependent hematopoietic cell linker.	0.688
ARHGAP27	CYTIP	ENSECAP00000039414	ENSECAP00000015032	Rho GTPase activating protein 27.	Cytohesin 1 interacting protein.	0.568
ARHGAP27	MRPS24	ENSECAP00000039414	ENSECAP00000037352	Rho GTPase activating protein 27.	Mitochondrial ribosomal protein S24.	0.525
ARHGAP27	MYO9A	ENSECAP00000039414	ENSECAP00000014509	Rho GTPase activating protein 27.	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.528
ARHGAP27	MYO9B	ENSECAP00000039414	ENSECAP00000009367	Rho GTPase activating protein 27.	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.530
ARHGAP27	NSMAF	ENSECAP00000039414	ENSECAP00000001442	Rho GTPase activating protein 27.	Neutral sphingomyelinase activation associated factor.	0.522
ARHGAP27	PLEKHM1	ENSECAP00000039414	ENSECAP00000051965	Rho GTPase activating protein 27.	Pleckstrin homology and RUN domain containing M1.	0.710
ARHGAP27	RDM1	ENSECAP00000039414	ENSECAP00000019620	Rho GTPase activating protein 27.	RAD52 motif containing 1.	0.697
ARHGAP27	VPS13D	ENSECAP00000039414	ENSECAP00000014589	Rho GTPase activating protein 27.	Vacuolar protein sorting 13 homolog D.	0.568
ARHGAP27	WDFY4	ENSECAP00000039414	ENSECAP00000033577	Rho GTPase activating protein 27.	WDFY family member 4.	0.586
CLNK	ARHGAP27	ENSECAP00000024317	ENSECAP00000039414	Cytokine dependent hematopoietic cell linker.	Rho GTPase activating protein 27.	0.688
CLNK	PLEKHM1	ENSECAP00000024317	ENSECAP00000051965	Cytokine dependent hematopoietic cell linker.	Pleckstrin homology and RUN domain containing M1.	0.486
CYTIP	ARHGAP27	ENSECAP00000015032	ENSECAP00000039414	Cytohesin 1 interacting protein.	Rho GTPase activating protein 27.	0.568
CYTIP	MRPS24	ENSECAP00000015032	ENSECAP00000037352	Cytohesin 1 interacting protein.	Mitochondrial ribosomal protein S24.	0.522
CYTIP	NSMAF	ENSECAP00000015032	ENSECAP00000001442	Cytohesin 1 interacting protein.	Neutral sphingomyelinase activation associated factor.	0.516
MRPS24	ARHGAP27	ENSECAP00000037352	ENSECAP00000039414	Mitochondrial ribosomal protein S24.	Rho GTPase activating protein 27.	0.525
MRPS24	CYTIP	ENSECAP00000037352	ENSECAP00000015032	Mitochondrial ribosomal protein S24.	Cytohesin 1 interacting protein.	0.522
MRPS24	NSMAF	ENSECAP00000037352	ENSECAP00000001442	Mitochondrial ribosomal protein S24.	Neutral sphingomyelinase activation associated factor.	0.473
MYO9A	ARHGAP27	ENSECAP00000014509	ENSECAP00000039414	Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Rho GTPase activating protein 27.	0.528
MYO9B	ARHGAP27	ENSECAP00000009367	ENSECAP00000039414	Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Rho GTPase activating protein 27.	0.530