STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHF2Pleckstrin homology and FYVE domain containing 2. (249 aa)    
Predicted Functional Partners:
PHIP
Pleckstrin homology domain interacting protein.
    
 
 0.482
PHF20L1
Uncharacterized protein.
      
 0.472
LMTK3
Lemur tyrosine kinase 3.
      
 0.461
SMDT1
Single-pass membrane protein with aspartate rich tail 1.
     
 0.449
ARHGEF11
Rho guanine nucleotide exchange factor 11.
      
 0.433
CHRNA2
Cholinergic receptor nicotinic alpha 2 subunit.
      
 0.433
NUCKS1
Nuclear casein kinase and cyclin dependent kinase substrate 1.
   
  
 0.432
PANX2
Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.
      
 0.432
MICU2
Mitochondrial calcium uptake 2.
   
 0.407
MICU1
Mitochondrial calcium uptake 1.
   
 0.407
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.