RAP2B protein (Equus caballus) - STRING interaction network

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Score

RAP2B

RAP2B, member of RAS oncogene family. (183 aa)

Predicted Functional Partners:

ITSN2

0.823

ITSN1

0.723

RAPGEF4

0.645

RAP1GAP

0.603

MET

0.559

RAP1GAP2

0.556

NF1

0.545

RAPGEF2

0.536

RASGRP4

0.535

FRMD7

0.533

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FRMD7	ITSN2	ENSECAP00000048687	ENSECAP00000023079	FERM domain containing 7.	Intersectin 2.	0.400
FRMD7	MET	ENSECAP00000048687	ENSECAP00000008993	FERM domain containing 7.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.468
FRMD7	RAP2B	ENSECAP00000048687	ENSECAP00000040256	FERM domain containing 7.	RAP2B, member of RAS oncogene family.	0.533
ITSN1	ITSN2	ENSECAP00000011417	ENSECAP00000023079	Intersectin 1.	Intersectin 2.	0.933
ITSN1	RAP2B	ENSECAP00000011417	ENSECAP00000040256	Intersectin 1.	RAP2B, member of RAS oncogene family.	0.723
ITSN2	FRMD7	ENSECAP00000023079	ENSECAP00000048687	Intersectin 2.	FERM domain containing 7.	0.400
ITSN2	ITSN1	ENSECAP00000023079	ENSECAP00000011417	Intersectin 2.	Intersectin 1.	0.933
ITSN2	MET	ENSECAP00000023079	ENSECAP00000008993	Intersectin 2.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.665
ITSN2	RAP2B	ENSECAP00000023079	ENSECAP00000040256	Intersectin 2.	RAP2B, member of RAS oncogene family.	0.823
MET	FRMD7	ENSECAP00000008993	ENSECAP00000048687	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	FERM domain containing 7.	0.468
MET	ITSN2	ENSECAP00000008993	ENSECAP00000023079	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Intersectin 2.	0.665
MET	RAP2B	ENSECAP00000008993	ENSECAP00000040256	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	RAP2B, member of RAS oncogene family.	0.559
MET	RASGRP4	ENSECAP00000008993	ENSECAP00000023443	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	RAS guanyl releasing protein 4.	0.493
NF1	RAP2B	ENSECAP00000007526	ENSECAP00000040256	Neurofibromin 1.	RAP2B, member of RAS oncogene family.	0.545
RAP1GAP	RAP2B	ENSECAP00000039283	ENSECAP00000040256	RAP1 GTPase activating protein.	RAP2B, member of RAS oncogene family.	0.603
RAP1GAP	RAPGEF4	ENSECAP00000039283	ENSECAP00000043922	RAP1 GTPase activating protein.	Rap guanine nucleotide exchange factor 4.	0.688
RAP1GAP2	RAP2B	ENSECAP00000046279	ENSECAP00000040256	RAP1 GTPase activating protein 2.	RAP2B, member of RAS oncogene family.	0.556
RAP1GAP2	RAPGEF4	ENSECAP00000046279	ENSECAP00000043922	RAP1 GTPase activating protein 2.	Rap guanine nucleotide exchange factor 4.	0.599
RAP2B	FRMD7	ENSECAP00000040256	ENSECAP00000048687	RAP2B, member of RAS oncogene family.	FERM domain containing 7.	0.533
RAP2B	ITSN1	ENSECAP00000040256	ENSECAP00000011417	RAP2B, member of RAS oncogene family.	Intersectin 1.	0.723