node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBFA2T2 | GET3 | ENSECAP00000041144 | ENSECAP00000005353 | CBFA2/RUNX1 partner transcriptional co-repressor 2. | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | 0.720 |
CBFA2T2 | NECAB3 | ENSECAP00000041144 | ENSECAP00000037289 | CBFA2/RUNX1 partner transcriptional co-repressor 2. | N-terminal EF-hand calcium binding protein 3. | 0.748 |
CBFA2T2 | TSEN15 | ENSECAP00000041144 | ENSECAP00000035522 | CBFA2/RUNX1 partner transcriptional co-repressor 2. | tRNA splicing endonuclease subunit 15. | 0.743 |
CBFA2T2 | UNKL | ENSECAP00000041144 | ENSECAP00000008626 | CBFA2/RUNX1 partner transcriptional co-repressor 2. | Unk like zinc finger. | 0.713 |
CBFA2T2 | USP37 | ENSECAP00000041144 | ENSECAP00000040458 | CBFA2/RUNX1 partner transcriptional co-repressor 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.675 |
GET3 | CBFA2T2 | ENSECAP00000005353 | ENSECAP00000041144 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | CBFA2/RUNX1 partner transcriptional co-repressor 2. | 0.720 |
GET3 | NECAB3 | ENSECAP00000005353 | ENSECAP00000037289 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | N-terminal EF-hand calcium binding protein 3. | 0.731 |
GET3 | PSMC5 | ENSECAP00000005353 | ENSECAP00000024764 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. | 0.539 |
GET3 | TSEN15 | ENSECAP00000005353 | ENSECAP00000035522 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | tRNA splicing endonuclease subunit 15. | 0.711 |
GET3 | UNKL | ENSECAP00000005353 | ENSECAP00000008626 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Unk like zinc finger. | 0.691 |
GET3 | USP37 | ENSECAP00000005353 | ENSECAP00000040458 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.635 |
JOSD2 | OTUD1 | ENSECAP00000034109 | ENSECAP00000023137 | Josephin domain containing 2. | OTU deubiquitinase 1. | 0.461 |
JOSD2 | USP37 | ENSECAP00000034109 | ENSECAP00000040458 | Josephin domain containing 2. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.620 |
NECAB3 | CBFA2T2 | ENSECAP00000037289 | ENSECAP00000041144 | N-terminal EF-hand calcium binding protein 3. | CBFA2/RUNX1 partner transcriptional co-repressor 2. | 0.748 |
NECAB3 | GET3 | ENSECAP00000037289 | ENSECAP00000005353 | N-terminal EF-hand calcium binding protein 3. | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] | 0.731 |
NECAB3 | TSEN15 | ENSECAP00000037289 | ENSECAP00000035522 | N-terminal EF-hand calcium binding protein 3. | tRNA splicing endonuclease subunit 15. | 0.739 |
NECAB3 | UNKL | ENSECAP00000037289 | ENSECAP00000008626 | N-terminal EF-hand calcium binding protein 3. | Unk like zinc finger. | 0.719 |
NECAB3 | USP37 | ENSECAP00000037289 | ENSECAP00000040458 | N-terminal EF-hand calcium binding protein 3. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.666 |
OTUD1 | JOSD2 | ENSECAP00000023137 | ENSECAP00000034109 | OTU deubiquitinase 1. | Josephin domain containing 2. | 0.461 |
OTUD1 | USP37 | ENSECAP00000023137 | ENSECAP00000040458 | OTU deubiquitinase 1. | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. | 0.616 |