STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNDC16Thioredoxin domain containing 16. (821 aa)    
Predicted Functional Partners:
NIPAL2
NIPA like domain containing 2.
   
  
 0.705
GAK
Cyclin G associated kinase.
   
 0.663
SLC26A11
Solute carrier family 26 member 11.
      
 0.625
TPST1
Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family.
    
 0.611
STXBP4
Syntaxin binding protein 4.
   
  
 0.586
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
      
 0.586
ZDHHC23
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
    
 
 0.585
DNAJB14
DnaJ heat shock protein family (Hsp40) member B14.
   
 0.579
MSRA
Methionine sulfoxide reductase A.
   
 0.571
ARHGEF10L
Rho guanine nucleotide exchange factor 10 like.
   
 
 0.569
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.