STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAFMAF bZIP transcription factor; Belongs to the bZIP family. (429 aa)    
Predicted Functional Partners:
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 
 0.901
NFE2L2
Nuclear factor, erythroid 2 like 2.
   
 0.756
BACH2
BTB domain and CNC homolog 2.
   
 0.745
JUN
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
0.683
NFE2L1
Nuclear factor, erythroid 2 like 1.
   
 0.665
KEAP1
Kelch like ECH associated protein 1.
      
 0.617
INS
Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.606
CUL3
Cullin 3; Belongs to the cullin family.
     
 0.587
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit.
    
 
 0.580
FOSL2
FOS like 2, AP-1 transcription factor subunit.
    
 
 0.577
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.