STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PELI3Pellino E3 ubiquitin protein ligase family member 3. (521 aa)    
Predicted Functional Partners:
IRAK1
Interleukin 1 receptor associated kinase 1.
    
 0.854
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.815
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 0.734
PROSER3
Proline and serine rich 3.
   
  
 0.696
IQCC
IQ motif containing C.
      
 0.696
IRAK2
Interleukin 1 receptor associated kinase 2.
    
 0.682
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.677
ENSECAP00000023797
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.677
KCNA10
Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family.
      
 0.570
LOC111770572
Uncharacterized protein.
   
  
 0.562
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.