STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAT2FRAT regulator of WNT signaling pathway 2. (233 aa)    
Predicted Functional Partners:
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 0.998
DVL1
Dishevelled segment polarity protein 1.
    
 0.936
DVL2
Dishevelled segment polarity protein 2.
    
 0.922
DVL3
Dishevelled segment polarity protein 3.
    
 0.916
FRAT1
Uncharacterized protein.
  
  
 
0.901
GSK3A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.740
OGFR
Opioid growth factor receptor.
    
 0.681
OGFRL1
Opioid growth factor receptor like 1.
    
 0.681
EHMT2
Euchromatic histone lysine methyltransferase 2.
      
 0.634
APC2
APC regulator of WNT signaling pathway 2.
     
 0.548
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.