STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHO2Pleckstrin homology domain containing O2. (499 aa)    
Predicted Functional Partners:
THEMIS2
Thymocyte selection associated family member 2.
   
  
 0.713
CMTR1
Cap methyltransferase 1.
      
 0.632
SASH1
SAM and SH3 domain containing 1.
   
  
 0.531
IL10RB
Interleukin 10 receptor subunit beta.
  
   
 0.520
TRIM14
Tripartite motif containing 14.
   
  
 0.482
CSRNP2
Cysteine and serine rich nuclear protein 2.
   
  
 0.462
FANCG
FA complementation group G.
  
     0.441
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.422
ITGAD
Integrin subunit alpha X; Belongs to the integrin alpha chain family.
   
  
 0.410
CTDSPL2
CTD small phosphatase like 2.
      
 0.406
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.