STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFA8Paneth cell-specific alpha-defensin 8. (98 aa)    
Predicted Functional Partners:
CYS1
Cystin 1.
      
 0.766
defl1
Defensin like 1.
      
 0.731
DEFB1
Defensin beta 1.
     
 0.540
ECATH-2
Myeloid cathelicidin 2.
   
  
 0.467
ECATH-3
Myeloid cathelicidin 3.
   
  
 0.449
LOC100064172
Uncharacterized protein.
   
  
 0.447
DEFB113
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.401
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.