STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC2Serine palmitoyltransferase long chain base subunit 2. (597 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
  
0.983
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 0.924
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 0.866
ORMDL3
ORMDL sphingolipid biosynthesis regulator 3.
    
 0.866
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 0.847
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.832
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.792
SGMS2
Sphingomyelin synthase 2.
   
  
 0.716
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
  
 
0.703
WDR93
WD repeat domain 93.
      
 0.683
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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