node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGEF12 | MET | ENSECAP00000045738 | ENSECAP00000008993 | Rho guanine nucleotide exchange factor 12. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.477 |
ARHGEF12 | PLXNB2 | ENSECAP00000045738 | ENSECAP00000042942 | Rho guanine nucleotide exchange factor 12. | Plexin B2. | 0.964 |
ARHGEF12 | RND1 | ENSECAP00000045738 | ENSECAP00000018486 | Rho guanine nucleotide exchange factor 12. | Rho family GTPase 1. | 0.704 |
ARHGEF12 | RRAS | ENSECAP00000045738 | ENSECAP00000025749 | Rho guanine nucleotide exchange factor 12. | RAS related. | 0.926 |
ARHGEF12 | SEMA4D | ENSECAP00000045738 | ENSECAP00000008174 | Rho guanine nucleotide exchange factor 12. | Semaphorin 4D; Belongs to the semaphorin family. | 0.589 |
MET | ARHGEF12 | ENSECAP00000008993 | ENSECAP00000045738 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Rho guanine nucleotide exchange factor 12. | 0.477 |
MET | PLXNB2 | ENSECAP00000008993 | ENSECAP00000042942 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Plexin B2. | 0.966 |
MET | RND1 | ENSECAP00000008993 | ENSECAP00000018486 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Rho family GTPase 1. | 0.710 |
MET | RRAS | ENSECAP00000008993 | ENSECAP00000025749 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | RAS related. | 0.636 |
MET | SEMA4A | ENSECAP00000008993 | ENSECAP00000006671 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4A; Belongs to the semaphorin family. | 0.705 |
MET | SEMA4B | ENSECAP00000008993 | ENSECAP00000020276 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4B; Belongs to the semaphorin family. | 0.611 |
MET | SEMA4C | ENSECAP00000008993 | ENSECAP00000013865 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4C; Belongs to the semaphorin family. | 0.606 |
MET | SEMA4D | ENSECAP00000008993 | ENSECAP00000008174 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4D; Belongs to the semaphorin family. | 0.789 |
MET | SEMA4F | ENSECAP00000008993 | ENSECAP00000048848 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Ssemaphorin 4F; Belongs to the semaphorin family. | 0.606 |
MET | SEMA4G | ENSECAP00000008993 | ENSECAP00000020077 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Semaphorin 4G; Belongs to the semaphorin family. | 0.606 |
PLXNB2 | ARHGEF12 | ENSECAP00000042942 | ENSECAP00000045738 | Plexin B2. | Rho guanine nucleotide exchange factor 12. | 0.964 |
PLXNB2 | MET | ENSECAP00000042942 | ENSECAP00000008993 | Plexin B2. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.966 |
PLXNB2 | RND1 | ENSECAP00000042942 | ENSECAP00000018486 | Plexin B2. | Rho family GTPase 1. | 0.978 |
PLXNB2 | RRAS | ENSECAP00000042942 | ENSECAP00000025749 | Plexin B2. | RAS related. | 0.975 |
PLXNB2 | SEMA4A | ENSECAP00000042942 | ENSECAP00000006671 | Plexin B2. | Semaphorin 4A; Belongs to the semaphorin family. | 0.979 |