STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (874 aa)    
Predicted Functional Partners:
HCN3
Hyperpolarization activated cyclic nucleotide gated potassium channel 3.
  
 
0.721
HCN1
Hyperpolarization activated cyclic nucleotide gated potassium channel 1.
  
  
 
0.549
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
  
  
 
0.548
KCNJ2
Potassium voltage-gated channel subfamily J member 2.
      
 0.478
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
    
 0.476
SYT2
Synaptotagmin 2.
      
 0.463
SYT1
Synaptotagmin 1.
      
 0.463
TBX5
T-box transcription factor 5.
   
  
 0.447
ATP2B3
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
  
 0.446
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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