STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP4Rho GTPase activating protein 4. (954 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
0.800
ARHGEF37
Rho guanine nucleotide exchange factor 37.
    
 
 0.769
STK10
Serine/threonine kinase 10.
   
  
 0.762
GAS7
Growth arrest specific 7.
   
 0.761
DNMBP
Dynamin binding protein.
   
 
 0.757
ARHGEF38
Rho guanine nucleotide exchange factor 38.
    
 
 0.750
WAS
WASP actin nucleation promoting factor.
   
 0.750
UBR3
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
      
 0.729
MTSS2
MTSS I-BAR domain containing 2.
    
 0.710
PACSIN2
Protein kinase C and casein kinase substrate in neurons 2.
   
 
 0.693
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.