STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXO31F-box protein 31. (567 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.920
CCND1
Cyclin D1; Belongs to the cyclin family.
    
 
 0.826
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.790
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.647
RBX1
Ring-box 1.
    
 0.615
CACUL1
CDK2 associated cullin domain 1; Belongs to the cullin family.
    
 0.544
CCND2
Cyclin D2; Belongs to the cyclin family.
   
 
 0.519
CCND3
Cyclin D3; Belongs to the cyclin family.
    
 
 0.514
RNF7
Ring finger protein 7.
    
  0.499
PEMT
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
   
  
 0.473
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.