STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIC1HIC ZBTB transcriptional repressor 1. (728 aa)    
Predicted Functional Partners:
SIRT1
Sirtuin 1.
    
 
 0.679
CHIC1
Cysteine rich hydrophobic domain 1.
      
 0.588
SLC5A8
Solute carrier family 5 member 8; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.539
CDK14
Cyclin dependent kinase 14; Belongs to the protein kinase superfamily.
   
 0.529
HMMR
Hyaluronan mediated motility receptor.
   
 0.498
MAN1B1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
      
 0.488
TFAP2B
Transcription factor AP-2 beta.
    
 
 0.487
TFAP2C
Transcription factor AP-2 gamma.
    
 
 0.487
TTYH3
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
     
 0.486
SPZ1
Spermatogenic leucine zipper 1.
    
 0.485
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.