STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (455 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.756
NANS
N-acetylneuraminate synthase.
 
   
 0.702
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.
    
 
 0.686
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.608
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.601
NEU4
Neuraminidase 4.
   
 0.574
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
   
 0.562
SNX5
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.560
SNX6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.560
SNX32
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.560
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.