STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)    
Predicted Functional Partners:
GNAO1
G protein subunit alpha o1.
    
 0.970
GNAI1
G protein subunit alpha i1.
   
 0.962
GNAI2
G protein subunit alpha i2.
    
 0.962
GNAI3
G protein subunit alpha i3.
    
 0.962
SLC6A3
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
 0.952
ARRB1
Arrestin beta 1.
   
 0.945
ARRB2
Arrestin beta 2.
   
 0.945
PPP2CB
Serine/threonine-protein phosphatase.
   
 0.915
PPP2R5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
     
 0.913
PPP2R1A
Protein phosphatase 2 scaffold subunit Aalpha.
   
 
  0.910
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.