STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF521Zinc finger protein 521. (1422 aa)    
Predicted Functional Partners:
TMEM241
Transmembrane protein 241.
      
 0.768
GOT1
Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-m [...]
    
 0.739
ANKRD29
Ankyrin repeat domain 29.
   
 0.713
SLC16A11
Solute carrier family 16 member 11.
    
 
 0.682
TMEM130
Transmembrane protein 130.
      
 0.618
RBM11
RNA binding motif protein 11.
   
 
 0.603
ZNF219
Zinc finger protein 219.
   
 
0.573
CDH22
Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins.
     
 0.569
GREB1L
GREB1 like retinoic acid receptor coactivator.
      
 0.568
CABLES1
Cdk5 and Abl enzyme substrate 1.
      
 0.566
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.