Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TNNI3Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (205 aa)    
Predicted Functional Partners:
TNNC1
Troponin C1, slow skeletal and cardiac type.
   
 0.998
TNNT2
Troponin T2, cardiac type.
   
 0.998
TNNT1
Troponin T1, slow skeletal type.
  
 0.996
TNNI2
Troponin I2, fast skeletal type.
  
 
0.954
TNNT3
Troponin T3, fast skeletal type.
   
 0.954
MYBPC3
Myosin binding protein C, cardiac.
   
 
 0.943
TNNC2
Troponin C2, fast skeletal type.
   
 0.928
MYL1
Myosin light chain 1.
   
 0.927
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.924
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
    
 0.924
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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