STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXC1Forkhead box C1. (548 aa)    
Predicted Functional Partners:
SOX18
SRY-box transcription factor 18.
   
 0.656
GATA2
GATA binding protein 2.
    
 0.612
LYVE1
Lymphatic vessel endothelial hyaluronan receptor 1.
    
 0.607
PITX2
Homeobox protein.
    
 
 0.605
GJC2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.588
ITGA9
Integrin subunit alpha 9; Belongs to the integrin alpha chain family.
   
  
 0.586
NFATC1
Nuclear factor of activated T cells 1.
   
 
 0.585
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
   
 
 0.553
EFNB2
Ephrin-B2; Belongs to the ephrin family.
      
 0.543
VEGFC
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
      
 0.540
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.