STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF25Rho guanine nucleotide exchange factor 25. (619 aa)    
Predicted Functional Partners:
STK17B
Serine/threonine-protein kinase 17B-like protein; Belongs to the protein kinase superfamily.
 
      0.776
GNA14
G protein subunit alpha 14.
    
 0.735
RHOB
Ras homolog family member B.
   
 0.702
RHOA
Transforming protein RhoA-like protein.
   
 0.702
GNAQ
G protein subunit alpha q.
    
 0.679
GNA11
G protein subunit alpha 11.
    
 0.679
RHOBTB3
Rho related BTB domain containing 3.
    
 0.653
GNA15
G protein subunit alpha 15.
    
 0.641
RND3
Rho family GTPase 3.
   
 0.584
ARHGEF28
Rho guanine nucleotide exchange factor 28.
   
 
 0.567
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.