STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBFOX2RNA binding fox-1 homolog 2. (476 aa)    
Predicted Functional Partners:
QKI
Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).
   
 
 0.871
RBM24
RNA binding motif protein 24.
  
 
 0.759
RBM38
RNA binding motif protein 38.
  
 
 0.728
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 0.722
NOVA2
NOVA alternative splicing regulator 2.
      
 0.714
PTBP2
Polypyrimidine tract binding protein 2.
    
 
 0.713
MBNL1
Muscleblind like splicing regulator 1.
    
 
 0.707
PTBP1
Polypyrimidine tract binding protein 1.
    
 
 0.693
ESRP2
Epithelial splicing regulatory protein 2.
     
 0.682
SRRM3
Serine/arginine repetitive matrix 3.
      
 0.674
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.