STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYBBCytochrome b-245 beta chain. (633 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.998
NCF1
Neutrophil cytosolic factor 1.
   
 0.993
NCF2
Neutrophil cytosolic factor 2.
   
 0.991
NOX4
NADPH oxidase 4.
  
 
0.979
NCF4
Neutrophil cytosolic factor 4.
   
 0.972
RAC2
Rac family small GTPase 2.
   
 0.960
RAC1
Rac family small GTPase 1.
   
 0.932
NOX1
NADPH oxidase 1.
  
  
0.924
MMP9
Matrix metallopeptidase 9.
   
 
 0.917
VCAM1
Vascular cell adhesion molecule 1.
   
 0.915
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.