STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAPN11Calpain 11; Belongs to the peptidase C2 family. (759 aa)    
Predicted Functional Partners:
CAST
Calpastatin.
   
 0.757
TKTL1
Transketolase like 1.
   
  
 0.728
CAPNS1
Calpain small subunit 1.
   
0.717
RAPGEF4
Rap guanine nucleotide exchange factor 4.
      
 0.678
GSR
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.608
ITSN2
Intersectin 2.
   
 
  0.532
IKBKE
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 
 0.528
SLC41A3
Solute carrier family 41 member 3.
      
 0.518
UMOD
Uromodulin.
    
 
 0.517
SPACA4
Sperm acrosome associated 4.
   
  
 0.500
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.