STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AUNIPAurora kinase A and ninein interacting protein. (360 aa)    
Predicted Functional Partners:
DTL
Denticleless E3 ubiquitin protein ligase homolog.
   
  
 0.693
ANLN
Anillin actin binding protein.
   
  
 0.633
AURKB
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 
 0.589
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
  
 0.577
UHRF1
Ubiquitin like with PHD and ring finger domains 1.
   
  
 0.538
ECT2
Epithelial cell transforming 2.
   
  
 0.535
KDM8
Lysine demethylase 8.
      
 0.487
LMNB2
Lamin B2; Belongs to the intermediate filament family.
   
  
 0.480
LOC100052168
Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...]
      
 0.470
JMJD6
Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.
      
 0.470
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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