LOC111772144 protein (Equus caballus) - STRING interaction network

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Score

LOC111772144

Uncharacterized protein. (399 aa)

Predicted Functional Partners:

HSP90AB1

0.518

HSP90AA1

0.518

SUGT1

0.514

TSC1

0.496

TRAP1

0.496

SHC4

0.491

SRM

0.483

HSP90B1

0.475

PFDN4

0.474

POLR3C

0.469

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HSP90AA1	HSP90AB1	ENSECAP00000025926	ENSECAP00000006887	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.904
HSP90AA1	HSP90B1	ENSECAP00000025926	ENSECAP00000029970	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Heat shock protein 90 beta family member 1.	0.936
HSP90AA1	LOC111772144	ENSECAP00000025926	ENSECAP00000047805	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	Uncharacterized protein.	0.518
HSP90AA1	SUGT1	ENSECAP00000025926	ENSECAP00000010916	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.996
HSP90AB1	HSP90AA1	ENSECAP00000006887	ENSECAP00000025926	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.904
HSP90AB1	HSP90B1	ENSECAP00000006887	ENSECAP00000029970	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	Heat shock protein 90 beta family member 1.	0.932
HSP90AB1	LOC111772144	ENSECAP00000006887	ENSECAP00000047805	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	Uncharacterized protein.	0.518
HSP90AB1	SUGT1	ENSECAP00000006887	ENSECAP00000010916	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.996
HSP90B1	HSP90AA1	ENSECAP00000029970	ENSECAP00000025926	Heat shock protein 90 beta family member 1.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.936
HSP90B1	HSP90AB1	ENSECAP00000029970	ENSECAP00000006887	Heat shock protein 90 beta family member 1.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.932
HSP90B1	LOC111772144	ENSECAP00000029970	ENSECAP00000047805	Heat shock protein 90 beta family member 1.	Uncharacterized protein.	0.475
HSP90B1	SUGT1	ENSECAP00000029970	ENSECAP00000010916	Heat shock protein 90 beta family member 1.	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.	0.816
HSP90B1	TRAP1	ENSECAP00000029970	ENSECAP00000037781	Heat shock protein 90 beta family member 1.	TNF receptor associated protein 1.	0.406
LOC111772144	HSP90AA1	ENSECAP00000047805	ENSECAP00000025926	Uncharacterized protein.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.518
LOC111772144	HSP90AB1	ENSECAP00000047805	ENSECAP00000006887	Uncharacterized protein.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.518
LOC111772144	HSP90B1	ENSECAP00000047805	ENSECAP00000029970	Uncharacterized protein.	Heat shock protein 90 beta family member 1.	0.475
LOC111772144	PFDN4	ENSECAP00000047805	ENSECAP00000033155	Uncharacterized protein.	Prefoldin subunit 4.	0.474
LOC111772144	POLR3C	ENSECAP00000047805	ENSECAP00000021276	Uncharacterized protein.	RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.469
LOC111772144	SHC4	ENSECAP00000047805	ENSECAP00000012836	Uncharacterized protein.	SHC adaptor protein 4.	0.491
LOC111772144	SRM	ENSECAP00000047805	ENSECAP00000017331	Uncharacterized protein.	Spermidine synthase; Belongs to the spermidine/spermine synthase family.	0.483