STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROBO4Roundabout guidance receptor 4. (1009 aa)    
Predicted Functional Partners:
SLIT2
Slit guidance ligand 2.
   
 0.947
SLIT3
Slit guidance ligand 3.
   
 0.901
SLIT1
Slit guidance ligand 1.
   
 0.857
GIT1
GIT ArfGAP 1.
   
  
 0.775
PXN
Paxillin.
   
  
 0.769
UNC5B
Unc-5 netrin receptor B.
   
 
0.754
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.744
NYX
Nyctalopin.
   
 0.722
EMCN
Endomucin.
   
  
 0.703
MMRN2
Multimerin 2.
   
 
 0.659
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.