STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FCARNatural cytotoxicity triggering receptor 1. (539 aa)    
Predicted Functional Partners:
NCR2
Natural cytotoxicity triggering receptor 2.
      
 0.941
KLRK1
Killer cell lectin like receptor K1.
   
  
 0.853
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
  
 0.714
KLRD1
C-type lectin domain-containing protein.
   
  
 0.697
CD244
CD244 molecule.
   
  
 0.688
CD27
CD27 molecule.
   
  
 0.666
LOC100051526
Uncharacterized protein.
   
  
 0.662
KLRG1
Killer cell lectin like receptor G1.
   
  
 0.659
CD4
CD4 molecule.
    
 
 0.642
NCR3
Natural cytotoxicity triggering receptor 3.
      
 0.640
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.