STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRMPD2FERM and PDZ domain containing 2. (1348 aa)    
Predicted Functional Partners:
REM1
RRAD and GEM like GTPase 1.
    
 0.992
PTPN20
Protein tyrosine phosphatase non-receptor type 20.
 
 
 
 0.924
PTPN18
Protein tyrosine phosphatase non-receptor type 18.
 
 
 
  0.613
CELF1
CUGBP Elav-like family member 1.
      
 0.574
DMPK
DM1 protein kinase.
    
 0.540
IFT80
Intraflagellar transport 80.
   
 0.539
TRAF3IP1
TRAF3 interacting protein 1.
    
 0.533
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
 0.532
IFT57
Intraflagellar transport 57.
    
 0.532
IFT172
Intraflagellar transport 172.
    
 0.519
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (28%) [HD]