LOC100066444 protein (Equus caballus) - STRING interaction network

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Score

LOC100066444

UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)

Predicted Functional Partners:

COMT

0.947

CYP1B1

0.943

CYP1A1

0.932

UGDH

0.931

SULT1E1

0.919

LOC100057251

0.908

AKR1D1

0.907

HSD11B1

0.907

GUSB

0.906

BLVRA

0.904

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKR1D1	HSD11B1	ENSECAP00000009863	ENSECAP00000016873	Aldo-keto reductase family 1 member D1.	Hydroxysteroid 11-beta dehydrogenase 1.	0.923
AKR1D1	LOC100057251	ENSECAP00000009863	ENSECAP00000054910	Aldo-keto reductase family 1 member D1.	Aldo-keto reductase family 1 member C23-like protein; NADP-dependent oxidoreductase involved in steroid metabolism. May act on various hydroxysteroids; Belongs to the aldo/keto reductase family.	0.902
AKR1D1	LOC100066444	ENSECAP00000009863	ENSECAP00000049914	Aldo-keto reductase family 1 member D1.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.907
BLVRA	LOC100066444	ENSECAP00000033526	ENSECAP00000049914	Biliverdin reductase A.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.904
COMT	CYP1A1	ENSECAP00000047104	ENSECAP00000012229	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.970
COMT	CYP1B1	ENSECAP00000047104	ENSECAP00000017028	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.979
COMT	LOC100066444	ENSECAP00000047104	ENSECAP00000049914	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.947
COMT	SULT1E1	ENSECAP00000047104	ENSECAP00000052928	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.435
CYP1A1	COMT	ENSECAP00000012229	ENSECAP00000047104	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	0.970
CYP1A1	CYP1B1	ENSECAP00000012229	ENSECAP00000017028	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.939
CYP1A1	HSD11B1	ENSECAP00000012229	ENSECAP00000016873	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta dehydrogenase 1.	0.921
CYP1A1	LOC100066444	ENSECAP00000012229	ENSECAP00000049914	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.932
CYP1A1	SULT1E1	ENSECAP00000012229	ENSECAP00000052928	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.938
CYP1B1	COMT	ENSECAP00000017028	ENSECAP00000047104	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.	0.979
CYP1B1	CYP1A1	ENSECAP00000017028	ENSECAP00000012229	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.939
CYP1B1	LOC100066444	ENSECAP00000017028	ENSECAP00000049914	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.943
GUSB	LOC100066444	ENSECAP00000012672	ENSECAP00000049914	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.906
HSD11B1	AKR1D1	ENSECAP00000016873	ENSECAP00000009863	Hydroxysteroid 11-beta dehydrogenase 1.	Aldo-keto reductase family 1 member D1.	0.923
HSD11B1	CYP1A1	ENSECAP00000016873	ENSECAP00000012229	Hydroxysteroid 11-beta dehydrogenase 1.	Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family.	0.921
HSD11B1	LOC100057251	ENSECAP00000016873	ENSECAP00000054910	Hydroxysteroid 11-beta dehydrogenase 1.	Aldo-keto reductase family 1 member C23-like protein; NADP-dependent oxidoreductase involved in steroid metabolism. May act on various hydroxysteroids; Belongs to the aldo/keto reductase family.	0.918