STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSECAP00000050821Thioredoxin domain-containing protein. (161 aa)    
Predicted Functional Partners:
TXNRD2
Thioredoxin reductase 2; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.900
PRDX3
Peroxiredoxin 3.
  
 0.898
MPST
Sulfurtransferase.
    
 0.887
PRDX5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.745
ENSECAP00000038121
Redoxin domain-containing protein.
   
 0.745
MSRA
Methionine sulfoxide reductase A.
   
 0.730
TXNDC8
Thioredoxin domain containing 8.
  
 
 0.712
TXNRD3
Thioredoxin reductase 3.
  
 0.662
COX5B
Cytochrome c oxidase subunit 5B.
   
  
 0.658
TXNIP
Thioredoxin interacting protein.
    
 0.641
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.