BPIFB4 protein (Equus caballus) - STRING interaction network

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Score

BPIFB4

BPI fold containing family B member 4. (660 aa)

Predicted Functional Partners:

LOC111769981

0.907

LOC111769983

0.833

BPIFA2

0.833

LATH

0.795

ZFAT

0.635

ASIP

0.632

LOC106781244

0.625

LOC106782421

0.625

LOC100069004

0.596

ENSECAP00000040754

0.596

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASIP	BPIFB4	ENSECAP00000003317	ENSECAP00000050984	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	BPI fold containing family B member 4.	0.632
ASIP	LOC111769981	ENSECAP00000003317	ENSECAP00000030033	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	BPI fold-containing family A member 2-like.	0.450
BPIFA2	BPIFB4	ENSECAP00000045131	ENSECAP00000050984	BPI fold containing family A member 2.	BPI fold containing family B member 4.	0.833
BPIFA2	LATH	ENSECAP00000045131	ENSECAP00000037152	BPI fold containing family A member 2.	Latherin; Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.	0.535
BPIFA2	LOC106781244	ENSECAP00000045131	ENSECAP00000020746	BPI fold containing family A member 2.	BPI1 domain-containing protein.	0.403
BPIFA2	LOC106782421	ENSECAP00000045131	ENSECAP00000037374	BPI fold containing family A member 2.	BPI1 domain-containing protein.	0.401
BPIFB4	ASIP	ENSECAP00000050984	ENSECAP00000003317	BPI fold containing family B member 4.	Agouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).	0.632
BPIFB4	BPIFA2	ENSECAP00000050984	ENSECAP00000045131	BPI fold containing family B member 4.	BPI fold containing family A member 2.	0.833
BPIFB4	ENSECAP00000040754	ENSECAP00000050984	ENSECAP00000040754	BPI fold containing family B member 4.	BPI1 domain-containing protein.	0.596
BPIFB4	LATH	ENSECAP00000050984	ENSECAP00000037152	BPI fold containing family B member 4.	Latherin; Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.	0.795
BPIFB4	LOC100069004	ENSECAP00000050984	ENSECAP00000039676	BPI fold containing family B member 4.	BPI1 domain-containing protein.	0.596
BPIFB4	LOC106781244	ENSECAP00000050984	ENSECAP00000020746	BPI fold containing family B member 4.	BPI1 domain-containing protein.	0.625
BPIFB4	LOC106782421	ENSECAP00000050984	ENSECAP00000037374	BPI fold containing family B member 4.	BPI1 domain-containing protein.	0.625
BPIFB4	LOC111769981	ENSECAP00000050984	ENSECAP00000030033	BPI fold containing family B member 4.	BPI fold-containing family A member 2-like.	0.907
BPIFB4	LOC111769983	ENSECAP00000050984	ENSECAP00000000218	BPI fold containing family B member 4.	BPI fold containing family A member 2.	0.833
BPIFB4	ZFAT	ENSECAP00000050984	ENSECAP00000036223	BPI fold containing family B member 4.	Zinc finger and AT-hook domain containing.	0.635
ENSECAP00000040754	BPIFB4	ENSECAP00000040754	ENSECAP00000050984	BPI1 domain-containing protein.	BPI fold containing family B member 4.	0.596
LATH	BPIFA2	ENSECAP00000037152	ENSECAP00000045131	Latherin; Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.	BPI fold containing family A member 2.	0.535
LATH	BPIFB4	ENSECAP00000037152	ENSECAP00000050984	Latherin; Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.	BPI fold containing family B member 4.	0.795
LATH	LOC111769981	ENSECAP00000037152	ENSECAP00000030033	Latherin; Major protein in sweat, has surfactant properties. Has a role in temperature regulation by having a capacity to make hydrophobic surfaces wettable and so can function in promoting spreading and evaporation of sweat; Belongs to the BPI/LBP/Plunc superfamily. Plunc family.	BPI fold-containing family A member 2-like.	0.634