STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MACF1Microtubule actin crosslinking factor 1. (7655 aa)    
Predicted Functional Partners:
UHRF1BP1
UHRF1 binding protein 1.
      
 0.883
DIO3
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.770
ITGB4
Integrin beta.
   
 0.731
C5H1orf74
Chromosome 5 C1orf74 homolog.
      
 0.692
MAPRE1
Microtubule associated protein RP/EB family member 1.
   
 
 0.649
VCL
Vinculin.
   
  
 0.623
JUP
Junction plakoglobin.
   
 0.593
MFN2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.585
MAP1B
Microtubule associated protein 1B.
   
  
 0.583
COL5A2
Collagen type V alpha 2 chain.
   
 0.567
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.