STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD6Ankyrin repeat domain 6. (797 aa)    
Predicted Functional Partners:
PRICKLE3
Prickle planar cell polarity protein 3.
   
 0.779
PRICKLE4
Prickle planar cell polarity protein 4.
   
 0.704
PRICKLE2
Prickle planar cell polarity protein 2.
   
 0.689
DVL1
Dishevelled segment polarity protein 1.
    
 0.678
PRICKLE1
Prickle planar cell polarity protein 1.
   
 0.661
VANGL1
Vang-like protein.
   
 0.644
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
   
 0.581
DYNLRB2
Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
     
 0.554
PTK7
Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.542
MDN1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
   
 0.541
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.