STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM121Transmembrane protein 121. (318 aa)    
Predicted Functional Partners:
SPIRE2
Spire type actin nucleation factor 2.
      
 0.740
PYCR2
Uncharacterized protein.
      
 0.740
PREB
Prolactin regulatory element binding.
      
 0.714
RD3L
Retinal degeneration 3 like.
      
 0.673
MVP
Major vault protein.
      
 0.592
SIVA1
Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
      
 0.577
AHNAK
AHNAK nucleoprotein.
      
 0.568
MAMDC4
MAM domain containing 4.
      
 0.563
SPRED1
Sprouty related EVH1 domain containing 1.
      
 0.540
POU3F1
POU domain protein.
      
 0.537
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.