STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFB4BDEFSN domain-containing protein. (65 aa)    
Predicted Functional Partners:
DEFB1
Defensin beta 1.
   
 
 0.960
LOC100629456
Beta-defensin 103A; Exhibits antimicrobial activity against Gram-positive and Gram-negative bacteria; Belongs to the beta-defensin family.
     
0.928
HSPB11
Heat shock protein family B (small) member 11.
      
 0.568
PTPRB
Protein tyrosine phosphatase receptor type B.
      
 0.534
CCR5
Chemokine receptor 5/2 large transcript; Belongs to the G-protein coupled receptor 1 family.
     
 0.477
CLEC4D
C-type lectin domain family 4 member D.
      
 0.475
DNAJC2
DnaJ heat shock protein family (Hsp40) member C2.
      
 0.473
DNAJC27
DnaJ heat shock protein family (Hsp40) member C27.
      
 0.472
CD84
CD84 molecule.
      
 0.471
CCR3
C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.
     
 0.432
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.