TNFRSF1B protein (Equus caballus) - STRING interaction network

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Score

TNFRSF1B

TNF receptor superfamily member 1B. (481 aa)

Predicted Functional Partners:

TNF

0.999

LTA

0.978

TRAF2

0.971

TNFRSF1A

0.960

DAXX

0.903

DAB2IP

0.901

TRAF1

0.723

TRAF3

0.686

TRAF5

0.638

TNFSF11

0.577

Your Current Organism:

Equus caballus

NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAB2IP	TNFRSF1B	ENSECAP00000024669	ENSECAP00000052749	DAB2 interacting protein.	TNF receptor superfamily member 1B.	0.901
DAB2IP	TRAF2	ENSECAP00000024669	ENSECAP00000011150	DAB2 interacting protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.923
DAXX	TNFRSF1A	ENSECAP00000018654	ENSECAP00000054554	Death domain associated protein.	TNF receptor superfamily member 1A.	0.919
DAXX	TNFRSF1B	ENSECAP00000018654	ENSECAP00000052749	Death domain associated protein.	TNF receptor superfamily member 1B.	0.903
LTA	TNF	ENSECAP00000000706	ENSECAP00000001460	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.966
LTA	TNFRSF1A	ENSECAP00000000706	ENSECAP00000054554	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	TNF receptor superfamily member 1A.	0.998
LTA	TNFRSF1B	ENSECAP00000000706	ENSECAP00000052749	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	TNF receptor superfamily member 1B.	0.978
LTA	TNFSF11	ENSECAP00000000706	ENSECAP00000014214	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	Tumor necrosis factor ligand superfamily member.	0.603
LTA	TRAF2	ENSECAP00000000706	ENSECAP00000011150	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.474
LTA	TRAF3	ENSECAP00000000706	ENSECAP00000043236	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.477
TNF	LTA	ENSECAP00000001460	ENSECAP00000000706	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	0.966
TNF	TNFRSF1A	ENSECAP00000001460	ENSECAP00000054554	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor superfamily member 1A.	0.999
TNF	TNFRSF1B	ENSECAP00000001460	ENSECAP00000052749	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor superfamily member 1B.	0.999
TNF	TNFSF11	ENSECAP00000001460	ENSECAP00000014214	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	Tumor necrosis factor ligand superfamily member.	0.648
TNF	TRAF1	ENSECAP00000001460	ENSECAP00000046165	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor-associated factor.	0.890
TNF	TRAF2	ENSECAP00000001460	ENSECAP00000011150	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.903
TNF	TRAF3	ENSECAP00000001460	ENSECAP00000043236	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.892
TNF	TRAF5	ENSECAP00000001460	ENSECAP00000005414	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.800
TNFRSF1A	DAXX	ENSECAP00000054554	ENSECAP00000018654	TNF receptor superfamily member 1A.	Death domain associated protein.	0.919
TNFRSF1A	LTA	ENSECAP00000054554	ENSECAP00000000706	TNF receptor superfamily member 1A.	Tumor necrosis factor ligand 1E; Belongs to the tumor necrosis factor family.	0.998