STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MVDMevalonate diphosphate decarboxylase. (497 aa)    
Predicted Functional Partners:
IDI1
Isopentenyl-diphosphate delta isomerase 1.
  
 
 0.998
MVK
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
 
 
 0.997
FDPS
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 0.993
PMVK
Phosphomevalonate kinase.
   
 
 0.989
GGPS1
Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.
  
 0.977
HAO1
Hydroxyacid oxidase 1.
    
 0.911
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
  
 
 0.902
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase decarboxylating-like protein; Belongs to the 3-beta-HSD family.
  
 
 0.890
SQLE
Squalene epoxidase.
   
  
 0.848
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.813
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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