STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEATR5BHEAT repeat containing 5B. (2100 aa)    
Predicted Functional Partners:
AP1G2
AP-1 complex subunit gamma.
   
 
 0.613
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
   
  
 0.595
API5
Tetratricopeptide repeat domain 17.
   
  
 0.568
AP4E1
AP-4 complex subunit epsilon; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
   
 
 0.524
LOC111769344
Glycine-N-acyltransferase like 3.
      
 0.493
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1.
      
 0.491
LYPLAL1
Lysophospholipase like 1.
   
  
 0.488
SMIM3
Small integral membrane protein 3.
      
 0.487
LHFPL1
LHFPL tetraspan subfamily member 1.
      
 0.487
FAM174A
Family with sequence similarity 174 member A.
      
 0.485
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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