STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLK10Kallikrein related peptidase 10; Belongs to the peptidase S1 family. (292 aa)    
Predicted Functional Partners:
RNF32
Ring finger protein 32.
      
 0.650
SPRR4
Small proline rich protein 4.
      
 0.633
SERPINB5
Serpin family B member 5; Belongs to the serpin family.
   
 0.609
KLK7
Kallikrein related peptidase 7; Belongs to the peptidase S1 family.
  
  
0.590
WFDC5
WAP four-disulfide core domain 5.
   
 0.582
LOC106782834
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
  
    0.534
EMC10
ER membrane protein complex subunit 10.
      
 0.518
CAPN7
Calpain 7; Belongs to the peptidase C2 family.
    
 
 0.517
PI3
Peptidase inhibitor 3.
      
 0.515
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
  0.496
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.